Open Access<p><em>HMGA2</em> Polymorphisms and Hepatoblastoma Susceptibility: A Five-Center Case-Control Study</p>
Author(s) -
Li Li,
Zhuo Zhang,
Zhen Yang,
Jinhong Zhu,
Xiaoli He,
Zhonghua Yang,
Jiao Zhang,
Yijuan Xin,
Jing He,
Tiesong Zhang
Publication year - 2020
Publication title -
pharmacogenomics and personalized medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.845
H-Index - 28
ISSN - 1178-7066
DOI - 10.2147/pgpm.s241100
Subject(s) - hepatoblastoma , medicine , single nucleotide polymorphism , genotype , odds ratio , gastroenterology , oncology , genetics , biology , gene
Hepatoblastoma is a rare disease. Its etiology remains obscure. No epidemiological reports have assessed the relationship of High Mobility Group A2 ( HMGA2 ) single nucleotide polymorphisms (SNPs) with hepatoblastoma risk. This case-control study leads as a pioneer to explore whether HMGA2 SNPs (rs6581658 A>G, rs8756 A>C, rs968697 T>C) could impact hepatoblastoma risk.