Open AccessResponse of Scalp and Skull Metastasis to Anti-PD-1 Antibody Combined with Regorafenib Treatment in a Sorafenib-Resistant Hepatocellular Carcinoma Patient and a Literature Review
Author(s) -
Xin Long,
Lei Zhang,
Wenqiang Wang,
Erlei Zhang,
Xing Lv,
Zhiyong Huang
Publication year - 2022
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s365652
Subject(s) - medicine , sorafenib , regorafenib , hepatocellular carcinoma , metastasis , skull , radiation therapy , brain metastasis , scalp , surgery , radiology , oncology , cancer , colorectal cancer
Scalp and skull metastasis of hepatocellular carcinoma (HCC) is extremely rare. Modalities for the treatment of this disease include craniotomy, radiotherapy and chemotherapy, which are unsatisfactory. We report a case of HCC with scalp and skull metastasis and review similar cases from the literature to accumulate experience for better management of this type of HCC metastasis.