Open AccessSerum Reactive Oxygen Species Modulator 1 as a Novel Predictive Biomarker for Resected Lung Adenocarcinoma: A Retrospective Pilot Study
Author(s) -
Betty L. Chang,
In-Sun Hwang,
Seung Hyeun Lee
Publication year - 2021
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s336399
Subject(s) - carcinoembryonic antigen , medicine , lung cancer , hazard ratio , adenocarcinoma , gastroenterology , confidence interval , biomarker , multivariate analysis , univariate analysis , oncology , cancer , biology , biochemistry
Reactive oxygen species modulator 1 (Romo1) is a key regulator of intracellular reactive oxygen species production. Previous studies have shown that Romo1 overexpression in tumor tissue is associated with poor clinical outcomes in various clinical settings for lung cancer treatment. The aim of the present study was to assess the predictive value of serum Romo1 in patients received curative resection for lung cancer.