Open AccessClinical Significance of the D-Loop Gene Mutation in Mitochondrial DNA in Laryngeal Cancer
Author(s) -
Lei Wang,
Hongwei Cheng,
Yanhui Zhou,
Min Ma
Publication year - 2021
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s304836
Subject(s) - microsatellite instability , mitochondrial dna , d loop , mutation , gene , point mutation , cancer , biology , gene mutation , microbiology and biotechnology , laryngeal neoplasm , mutation rate , genetics , dna sequencing , polymerase chain reaction , microsatellite , allele
The aim of the present study was to investigate the D-loop gene mutation and microsatellite instability in the mitochondrial DNA (mtDNA) and the correlation with the clinical and pathological parameters in laryngeal cancer.