Open AccessComprehensive Analysis of the Relationship Between Metabolic Reprogramming and Immune Function in Prostate Cancer
Author(s) -
Weijie Xie,
Huan Guo,
Jiawei Zhang,
Li Hu,
Yuqi Wu,
Xiangwei Wang
Publication year - 2021
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s304298
Subject(s) - prostate cancer , immune system , cancer research , biology , glycolysis , kegg , tumor microenvironment , cd8 , prostate , cancer cell , gene expression , cancer , immunology , transcriptome , gene , endocrinology , genetics , metabolism
Prostate cancer is the most common malignant urinary tumor among men. Treatments are currently unsatisfactory for advanced prostate cancer. Cancer biology remains the basis for developing new antitumor drugs. Therefore, it is crucial to study the metabolic reprogramming, immune microenvironment, and immune evasion of tumors. This study aimed to clarify the relationship between tumor glycolysis and immune function in prostate cancer.