Open AccessLncRNA ST8SIA6-AS1 Promotes Cholangiocarcinoma Progression by Suppressing the miR-145-5p/MAL2 Axis
Author(s) -
Jin He,
Hongxian Yan,
Sha Xin Wei,
Guoyong Chen
Publication year - 2021
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s299634
Subject(s) - apoptosis , cancer research , cell growth , function (biology) , luciferase , cell , cell culture , biology , microrna , microbiology and biotechnology , medicine , gene , transfection , genetics
The tumor-promoting roles of ST8SIA6-AS1 and miR-145-5p have been found in several cancers, but their function in cholangiocarcinoma (CHOL) remains speculative. The purpose of this study was to examine the regulatory functions of the ST8SIA6-AS1/MAL2/miR-145-5p pathway in CHOL progression.