Open AccessCDH11 Regulates Adhesion and Transcellular Migration of Tongue Squamous Cell Carcinoma
Author(s) -
Bi-Tan Zheng,
Qingling Li,
Ting Lan,
Jian Xie,
Youguang Lu,
Bogong Su
Publication year - 2021
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s298614
Subject(s) - cadherin , cell migration , cancer research , tongue , cell , apoptosis , morphogenesis , biology , metastasis , cancer , pathology , microbiology and biotechnology , medicine , gene , genetics
CDH11, as a member of cadherins, mediates homotypic cell adhesion. Some studies have shown that CDH11 plays an important role in the development of tumors, especially in the processes of tumor invasion and metastasis. While features of CDH11 in tongue squamous cell carcinoma (TSCC) are still indeterminate, the purpose of the present study is to explore the role of CDH11 in TSCC.