Open AccessCirculating Tumor Cells Undergoing the Epithelial–Mesenchymal Transition: Influence on Prognosis in Cytokeratin 19-Positive Hepatocellular Carcinoma
Author(s) -
Qian Zhang,
Wan-Ting Xing,
Jie Zhang,
Jinwen Hu,
LuNan Qi,
BangDe Xiang
Publication year - 2021
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s298576
Subject(s) - cytokeratin , medicine , circulating tumor cell , hepatocellular carcinoma , epithelial–mesenchymal transition , immunohistochemistry , pathology , oncology , gastroenterology , mesenchymal stem cell , cancer , metastasis
The purpose of this study was to elucidate the relationship between cytokeratin 19 (CK19) expression and levels of circulating tumor cells (CTCs) in preoperative peripheral blood of patients with hepatocellular carcinoma (HCC), and the potential influence of that relationship on prognosis.