Open AccessConstruction of the Prediction Model for Locally Advanced Rectal Cancer Following Neoadjuvant Chemoradiotherapy Based on Pretreatment Tumor-Infiltrating Macrophage-Associated Biomarkers
Author(s) -
Xing Liu,
Shuping Zheng,
Yong Peng,
Jinfu Zhuang,
Yuanfeng Yang,
Yunlu Xu,
Guoxian Guan
Publication year - 2021
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s297263
Subject(s) - medicine , colorectal cancer , proportional hazards model , oncology , chemoradiotherapy , cd163 , pathological , cd68 , neoadjuvant therapy , stage (stratigraphy) , cancer , gastroenterology , immunohistochemistry , macrophage , paleontology , biochemistry , chemistry , breast cancer , in vitro , biology
To assess the value of macrophage-related biomarkers (CD163, CD68, MCSF, and CCL2) for predicting the response to neo-chemoradiotherapy (NCRT) and the prognosis of locally advanced rectal cancer (LARC).