Open AccessSerum Exosomal miRNA-1226 as Potential Biomarker of Pancreatic Ductal Adenocarcinoma
Author(s) -
Cheng Wang,
Jianhua Wang,
Wenjing Cui,
Yongkang Liu,
Hao Zhou,
Yajie Wang,
Xin Chen,
Xiao Chen,
Zhongqiu Wang
Publication year - 2021
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s296816
Subject(s) - microrna , exosome , pancreatic cancer , biomarker , cancer research , medicine , pancreatic ductal adenocarcinoma , microvesicles , cancer , oncology , pathology , biology , gene , biochemistry
Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer-related mortality and it is urgent to find biomarkers for early detection of PDAC. Exosomal miRNAs are useful biomarkers for cancer detection. The aims of this study were to investigate the potential role of serum exosomal miRNA in detection of PDAC and to analyze the correlation between the levels of exosome miRNA and the tumor biological behaviors.