Open AccessHigh Expression of SLC41A3 Correlates with Poor Prognosis in Hepatocellular Carcinoma
Author(s) -
Qian Li,
Dan-Lei Xiong,
Heng Wang,
Weili Jin,
Yingyu Ma,
Xiaoming Fan
Publication year - 2021
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s296187
Subject(s) - hepatocellular carcinoma , immunohistochemistry , medicine , proportional hazards model , oncology , survival analysis , cancer , metastasis , cancer research , pathology
SLC41A3 is a member of the solute carrier family 41 (SLC41) and is involved in many cellular processes as a magnesium ion transporter. Although it plays an important role in cancer formation and development, the correlation between the expression of SLC41A3 and the occurrence and prognosis of hepatocellular carcinoma (HCC) remains unclear. Therefore, this study was focused on the evaluation of the relationship between SLC41A3 and the development and prognosis of HCC.