Open AccessExpression of p16, p53, and TLR9 in HPV-Associated Head and Neck Squamous Cell Carcinoma: Clinicopathological Correlations and Potential Prognostic Significance
Author(s) -
Shu Hsien Wang,
Xibing Zhuang,
Caixia Gao,
Tiankui Qiao
Publication year - 2021
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s293163
Subject(s) - head and neck squamous cell carcinoma , immunohistochemistry , medicine , oncology , tlr9 , hazard ratio , cancer research , proportional hazards model , cancer , head and neck cancer , pathology , biology , gene expression , gene , confidence interval , biochemistry , dna methylation
To investigate the association of human papillomavirus (HPV) status with p16, p53, and TLR9 expression in head and neck squamous cell carcinoma (HNSCC) and to evaluate these proteins as potential surrogate prognostic markers.