Open AccessLong Noncoding RNA JAKMIP2-AS1 Promotes the Growth of Colorectal Cancer and Indicates Poor Prognosis
Author(s) -
Tianyi Ma,
Tianyu Qiao,
Ziming Yuan,
Guiyu Wang,
Rui Huang,
Meng Wang,
Hanqing Hu,
Yihao Zhu,
Xiaoming Zou,
Xishan Wang
Publication year - 2021
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s289617
Subject(s) - gene knockdown , colorectal cancer , rna interference , cell growth , cancer research , biology , long non coding rna , in vivo , proliferating cell nuclear antigen , cell culture , cancer , context (archaeology) , downregulation and upregulation , rna , microbiology and biotechnology , gene , genetics , paleontology
The identification of cancer-associated long noncoding RNAs and the investigation of their molecular and biological functions are important for understanding the molecular biology and progression of cancer. JAKMIP2-AS1 has not been reported in the literature, especially in the context of colorectal cancer. The aim of the present study was to examine the expression pattern of JAKMIP2-AS1 in colorectal cancer (CRC) and evaluate its biological role and clinical significance in tumor progression.