Open AccessACTL6A Promotes the Proliferation of Esophageal Squamous Cell Carcinoma Cells and Correlates with Poor Clinical Outcomes
Author(s) -
Rui-Zhe Li,
Yunyun Li,
Hui Qin,
Shanshan Li
Publication year - 2021
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s288807
Subject(s) - downregulation and upregulation , cancer research , gene knockdown , cyclin d1 , cell cycle , cell growth , flow cytometry , immunohistochemistry , cell , cyclin dependent kinase 2 , biology , cell culture , chemistry , microbiology and biotechnology , immunology , biochemistry , gene , genetics
ACTL6A, a regulatory subunit of ATP-dependent chromatin-remodeling complexes SWI/SNF, has been identified as a central oncogenic driver in many tumor types.