Open AccessAberrant SLC6A14 Expression Promotes Proliferation and Metastasis of Colorectal Cancer via Enhancing the JAK2/STAT3 Pathway
Author(s) -
Hongli Mao,
Jinxiu Sheng,
Jinlin Jia,
Chang Yun Wang,
Shanfeng Zhang,
Hongle Li,
Fucheng He
Publication year - 2021
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s288709
Subject(s) - cancer research , cell growth , chemistry , ectopic expression , biology , biochemistry , gene
Solute carrier family 6 member 14 (SLC6A14) is a high-capacity amino acid transporter in mammalian cells. It has gained increasing attention for its potential involvement in the progression and metabolic reprogramming of various malignant tumors. However, the role of SLC6A14 in colorectal cancer (CRC) remains unclear.