Open AccessIncreased Collagen Type V α2 (COL5A2) in Colorectal Cancer is Associated with Poor Prognosis and Tumor Progression
Author(s) -
Jie Wang,
Yihua Jiang,
Pengyuan Yang,
Liang Feng
Publication year - 2021
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s288422
Subject(s) - colorectal cancer , wnt signaling pathway , cancer , tissue microarray , medicine , microsatellite instability , oncology , cancer research , biology , gene , genetics , microsatellite , allele
Colorectal cancer (CRC) is the third most common cancer in males and the second in females worldwide with very poor prognosis. Extracellular matrix proteins like collagens play important roles in cancer progression. Collagen type V α2 (COL5A2) is increased in several cancers but its role in cancer remains unclear.