Open AccessPretreatment Albumin-to-Fibrinogen Ratio Independently Predicts Chemotherapy Response and Prognosis in Patients with Locally Advanced Rectal Cancer Undergoing Total Mesorectal Excision After Neoadjuvant Chemoradiotherapy
Author(s) -
Hongzhi Li,
Honggang Wang,
Shanshan Shao,
Yawen Gu,
Juan Yao,
Junxing Huang
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s288265
Subject(s) - medicine , total mesorectal excision , colorectal cancer , chemoradiotherapy , fibrinogen , chemotherapy , albumin , oncology , neoadjuvant therapy , surgery , cancer , breast cancer
Neoadjuvant chemoradiotherapy (nCRT) followed by surgery of total mesorectal excision (TME) is currently accepted as the standard treatment for locally advanced rectal cancer (LARC). This study aimed to investigate the potential prognostic factors, including the albumin-to-fibrinogen ratio (AFR) for LARC patients.