Open AccessCirc-PITX1 Promotes the Progression of Non-Small Cell Lung Cancer Through Regulating the miR-1248/CCND2 Axis
Author(s) -
Qianyu Yue,
Yanyan Xu,
Xiaoli Duan,
Shenglan Wang,
Jingman Qiu,
Biao Qian,
Yunhui Zhang
Publication year - 2021
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s286820
Subject(s) - cyclin d2 , cell growth , cell cycle , apoptosis , cancer research , downregulation and upregulation , glutamine , chemistry , microrna , glutaminase , flow cytometry , biology , microbiology and biotechnology , cyclin d1 , biochemistry , amino acid , gene
Circular RNA (circRNA) is a key regulator of cancer, and it has been proved to be involved in the regulation of cancer progression including non-small cell lung cancer (NSCLC). Circ-PITX1 was found to be a significantly upregulated circRNA in NSCLC, and its role and potential mechanism in NSCLC progression deserve further investigation.