Open AccessMiRNA-223-3p Affects Mantle Cell Lymphoma Development by Regulating the CHUK/NF-ƘB2 Signaling Pathway
Author(s) -
Jingjing Yuan,
Qing Zhang,
Shengsheng Wu,
Suran Yan,
Ruihua Zhao,
Yuxin Sun,
Xiaoxu Tian,
Keshu Zhou
Publication year - 2021
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s283486
Subject(s) - gene knockdown , microrna , cancer research , apoptosis , cell growth , biology , flow cytometry , microbiology and biotechnology , gene , genetics
Mantle cell lymphoma (MCL) is an aggressive malignancy that accounts for 5-10% of non-Hodgkin's lymphoma. MiRNA-223-3p has been demonstrated to be down-regulated in MCL and is a useful prognostic factor. However, little is known about underlying molecular mechanism of miRNA-233-3p in MCL.