Open AccessCircular RNA circARPP21 Acts as a Sponge of miR-543 to Suppress Hepatocellular Carcinoma by Regulating LIFR
Author(s) -
Yun Gu,
Fan Wu,
Hao Wang,
Jiang Chang,
Yu Zhang,
Xiangcheng Li
Publication year - 2021
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s283026
Subject(s) - leukemia inhibitory factor receptor , hepatocellular carcinoma , microrna , cancer research , gene silencing , circular rna , metastasis , biomarker , competing endogenous rna , gene knockdown , rna interference , real time polymerase chain reaction , luciferase , medicine , biology , long non coding rna , rna , transfection , cancer , cell culture , leukemia inhibitory factor , gene , biochemistry , interleukin 6 , genetics , cytokine
A large body of evidence has shown that circular RNAs (circRNAs) play a significant role in the progression of some malignant cancers, including hepatocellular carcinoma (HCC). However, the complex mechanism of circRNAs in hepatocellular carcinoma has not been clarified.