Open AccessLINC00460 Promotes Cell Proliferation, Migration, Invasion, and Epithelial-Mesenchymal Transition of Head and Neck Squamous Cell Carcinoma via miR-320a/BGN Axis
Author(s) -
Yifan Yang,
Wang Ru,
Feng Ling,
Hongzhi Ma,
Jugao Fang
Publication year - 2021
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s282947
Subject(s) - head and neck squamous cell carcinoma , gene knockdown , downregulation and upregulation , cell growth , epithelial–mesenchymal transition , cancer research , cell , cell culture , biology , cell migration , western blot , cancer , head and neck cancer , gene , biochemistry , genetics
Long non-coding RNAs (lncRNAs) play critical roles in cancer onset and development, including head and neck squamous cell carcinoma (HNSCC). This study aimed to investigate the biological role of LINC00460 and the mechanisms underlying epithelial-mesenchymal transition (EMT) in HNSCC.