Open AccessBiological Behavior and Lipid Metabolism of Colon Cancer Cells are Regulated by a Combination of Sterol Regulatory Element-Binding Protein 1 and ATP Citrate Lyase
Author(s) -
Zhendong Qiu,
Wei Deng,
Yupu Hong,
Liang Zhao,
Man Li,
Yongjun Guan,
Ying-ru Su,
Chen Chen,
Qiao Shi,
Jia Yu,
Weixing Wang
Publication year - 2021
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s282906
Subject(s) - sterol regulatory element binding protein , gene knockdown , atp citrate lyase , lipid metabolism , cell growth , viability assay , chemistry , microbiology and biotechnology , cell , biology , apoptosis , biochemistry , transcription factor , citrate synthase , gene , enzyme
To research the effects of ATP citrate lyase (ACLY) and Sterol-regulatory element binding protein 1 (SREBP1) on the biology and lipid metabolism of colorectal cancer cells.