Open AccessGADD45B Facilitates Metastasis of Ovarian Cancer Through Epithelial–Mesenchymal Transition
Author(s) -
Lanqing Gong,
Lei Cai,
Guodong Li,
Jing Cai,
Xiaoqing Yi
Publication year - 2021
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s281450
Subject(s) - epithelial–mesenchymal transition , kegg , ovarian cancer , vimentin , immunohistochemistry , cancer research , metastasis , biology , blot , downregulation and upregulation , cancer , gene , gene expression , immunology , transcriptome , genetics
Growth arrest and DNA-damage-inducible 45 beta ( GADD45B ) is overexpressed and is associated with poor clinical outcomes in many human cancers, but the clinical implication of GADD45B in epithelial ovarian cancer (EOC) remains unclear.