Open AccessDepletion of hsa_circ_0000144 Suppresses Oxaliplatin Resistance of Gastric Cancer Cells by Regulating miR-502-5p/ADAM9 Axis
Author(s) -
Haifeng Gao,
Jiajia Xu,
Fen Qiao,
Xue Lin
Publication year - 2021
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s281238
Subject(s) - flow cytometry , gene knockdown , oncogene , cell growth , microbiology and biotechnology , apoptosis , cancer research , microrna , chemistry , cancer cell , in vivo , biology , cancer , cell cycle , gene , biochemistry , genetics
Circular RNAs (circRNAs) have been disclosed to exert important roles in human cancers, including gastric cancer (GC). CircRNA hsa_circ_0000144 was identified as an oncogene in GC development. The aim of our study was to explore the role of hsa_circ_0000144 in oxaliplatin (OXA) resistance of GC.