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Circular RNAs (circRNAs) are novel clusters of endogenous noncoding RNAs (ncRNAs) that are involved in the regulation of multiple biological processes in diverse types of cancers. However, the roles and precise mechanisms of circRNAs in renal cell carcinoma (RCC) occurrence and progression have not been clearly elucidated.

oncotargets and therapy

&lt;p&gt;Upregulated &lt;em&gt;circPDK1&lt;/em&gt; Promotes RCC Cell Migration and Invasion by Regulating the &lt;em&gt;miR-377-3P-NOTCH1&lt;/em&gt; Axis in Renal Cell Carcinoma&lt;/p&gt;