Open Access<p>Huaier Suppresses the Hepatocellular Carcinoma Cell Cycle by Regulating Minichromosome Maintenance Proteins</p>
Author(s) -
Yongjie Niu,
Shan Liang,
Han Gao,
Congcong Zhang,
Zhiliang Qian,
Zhixian Wang,
Xin Xu,
Xiao Zhang,
Jiayi Wang,
Lifang Ma,
Liyun Chen,
Yongchun Yu
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s279723
Subject(s) - hepatocellular carcinoma , western blot , cell cycle , cancer research , biology , proteomics , cancer , gene , biochemistry , genetics
Hepatocellular carcinoma (HCC) is a common malignant tumor with limited treatment. Our previous studies demonstrated that Huaier enhanced chemotherapy sensitivity and restrained HCC proliferation. This study aimed to identify differentially expressed proteins with Huaier treatment in HCC cells, providing molecular targets for future targeted therapy of HCC.