Open Access<p>Cytochrome C Oxidase Assembly Factor 1 Homolog Predicts Poor Prognosis and Promotes Cell Proliferation in Colorectal Cancer by Regulating PI3K/AKT Signaling</p>
Author(s) -
Yan Xue,
Peidong Li,
Xuemei Tang,
Zaihua Yan,
Shu-Sen Xia,
Hongpeng Tian,
Zuo-Liang Liu,
Tong Zhou,
Xuegui Tang,
Guangjun Zhang
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s279024
Subject(s) - gene knockdown , cancer research , pi3k/akt/mtor pathway , cell growth , small hairpin rna , protein kinase b , microarray analysis techniques , colorectal cancer , cancer , biology , carcinogenesis , medicine , apoptosis , signal transduction , gene expression , gene , microbiology and biotechnology , genetics
Colorectal cancer (CRC) is one of the most common malignancies in the world. The prognosis of advanced CRC is still poor. The purpose of this study was to identify a gene expression profile associated with CRC that may contribute to the early diagnosis of CRC and improve patient prognosis.