Open Access<p>TRPS1 and YAP1 Regulate Cell Proliferation and Drug Resistance of Osteosarcoma via Competitively Binding to the Target of circTADA2A – miR-129-5p</p>
Author(s) -
Jinyu Zhang,
Xiang Ji,
Ruiqi Zhou,
Yichi Zhou
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s276953
Subject(s) - gene knockdown , yap1 , cell growth , downregulation and upregulation , cancer research , osteosarcoma , chemistry , apoptosis , medicine , microbiology and biotechnology , biology , transcription factor , biochemistry , gene
The yes-associated protein (YAP) and trichorhinophalangeal syndrome 1 (TRPS1) have been reported to account for the pathogenesis of cancers and may play an important role in osteosarcoma (OS). This study intended to investigate the modulatory effect and relationship of TRPS1 and YAP1 in OS cells.