Open Access<p>Mutational Characterization and Potential Prognostic Biomarkers of Chinese Patients with Esophageal Squamous Cell Carcinoma</p>
Author(s) -
Nan Zhang,
Junping Shi,
Xiaoliang Shi,
Wenting Chen,
Junfeng Liu
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s275688
Subject(s) - cdkn2a , medicine , fgf19 , esophageal cancer , esophageal squamous cell carcinoma , oncology , lymph , cancer research , metastasis , carcinoma , cancer , pathology , receptor , fibroblast growth factor
Esophageal squamous cell carcinoma (ESCC) is the most common type of esophageal cancer in China and the 5-year mortality rate is up to 70%. Studies on the ESCC genetic landscape are needed to further explore clinical therapeutic strategies. In this study, we evaluated the genetic landscape of ESCC to aid the search for clinical therapeutic strategies.