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Glioblastoma (GBM) is the most lethal primary cancer in adult central nervous system, and new strategies are desperately needed. The secretory pathway kinase or kinase-like proteins (SPKKPs) have been shown to mediate multiple physiological functions by phosphorylating extracellular proteins and proteoglycans. However, their roles in cancers, especially GBM, remain poorly defined.

oncotargets and therapy

&lt;p&gt;Secretory Pathway Kinase &lt;em&gt;FAM20C&lt;/em&gt;, a Marker for Glioma Invasion and Malignancy, Predicts Poor Prognosis of Glioma&lt;/p&gt;