Open Access<p>Neuropilin-1 Interacts with Fibronectin-1 to Promote Epithelial–Mesenchymal Transition Progress in Gastric Cancer</p>
Author(s) -
Chao Wu,
Menghua Zeng,
Gang Liao,
Kun Qian,
Hui Li
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s275327
Subject(s) - neuropilin 1 , cancer research , metastasis , fibronectin , cancer , epithelial–mesenchymal transition , cancer cell , medicine , gene knockdown , tumor progression , cell migration , chemistry , cell , apoptosis , vascular endothelial growth factor , biochemistry , vegf receptors
Neuropilin-1 (NRP1) binds to many ligands and co-receptors and affects cell survival and migration, which is essential for tumor progression. However, there are still largely unknowns about how NRP1 affects the epithelial-mesenchymal transition (EMT)-related malignant progression in gastric cancer.