Open Access<p>High Expression of CD39 is Associated with Poor Prognosis and Immune Infiltrates in Clear Cell Renal Cell Carcinoma</p>
Author(s) -
Jie Wu,
Yu-Chen Wang,
Wen Xu,
Wen Luo,
Fang Wan,
Ye Zhang,
Dingwei Ye,
Yuan Qu,
Yi Ping Zhu
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s272553
Subject(s) - clear cell renal cell carcinoma , medicine , tumor microenvironment , cancer research , tumor infiltrating lymphocytes , immune checkpoint , immune system , foxp3 , renal cell carcinoma , oncology , immunotherapy , immunology
The cell-surface ectonucleotidase CD39 is a key molecule of the immunosuppressive adenosine pathway within the tumor microenvironment. However, the relationship between CD39 and clear cell renal cell carcinoma (ccRCC) is rarely reported and still remains unclear.