Open Access<p>Overexpression of <em>GIHCG</em> is Associated with a Poor Prognosis and Immune Infiltration in Hepatocellular Carcinoma</p>
Author(s) -
Shiying Xiao,
Shanzhou Huang,
Jie Yang
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s271966
Subject(s) - hepatocellular carcinoma , infiltration (hvac) , immune system , medicine , cancer research , gastroenterology , immunology , physics , thermodynamics
Hepatocellular carcinoma (HCC) is one of the most commonly diagnosed digestive cancers and the fourth leading cause of death worldwide. Long noncoding RNAs (lncRNAs) with key roles in HCC development and progression have emerged and are used in the diagnosis and prognostic prediction of HCC. The lncRNA gradually increased during hepatocarcinogenesis ( GIHCG ) is a novel lncRNA with aberrant expression in many tumors, but its prognostic value and biological role in HCC have not been fully studied. Thus, the aim of this study was to explore the expression pattern and potential biological role of GIHCG in HCC.