Open Access<p>MicroRNA Derived from Circulating Exosomes as Noninvasive Biomarkers for Diagnosing Renal Cell Carcinoma</p>
Author(s) -
Chutian Xiao,
Wenjie Lai,
Weian Zhu,
Hua Wang
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s271606
Subject(s) - microvesicles , renal cell carcinoma , microrna , biomarker , exosome , medicine , kidney cancer , cancer , diagnostic biomarker , carcinoma , cancer biomarkers , cancer research , oncology , pathology , gene , biology , biochemistry
Renal cell carcinoma (RCC) is the most common type of kidney cancer in adults. Exosomes are membrane-enclosed extracellular vesicles, and exosomal RNA can be a biomarker for cancer diagnosis and prognosis in RCC patients. We aim to identify differences in miRNA expression profiles in peripheral blood exosomes between RCC patients and healthy subjects as well as to investigate novel markers of RCC.