Open Access<p>LncRNA XIST Inhibits the Progression of Oral Squamous Cell Carcinoma via Sponging miR-455-3p/BTG2 Axis</p>
Author(s) -
Qingbin Li,
Qiang Sun,
Baoyu Zhu
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s267937
Subject(s) - xist , long non coding rna , competing endogenous rna , cancer research , microrna , rna , biology , western blot , cell growth , microbiology and biotechnology , gene , x inactivation , genetics , x chromosome
Oral squamous cell carcinoma (OSCC) is one of the most common cancers, accounting for over 90% of malignant lesions in the oral cavity. Long non-coding RNAs play an important role in the development of OSCC. This study aimed to investigate the effects of lncRNA XIST on the malignant behaviors of OSCC cells and its possible molecular mechanisms.