Open Access<p>The Role of Dynamic ctDNA Monitoring During Combination Therapies of BRAF V600E-Mutated Metastatic Colorectal Cancer: A Case Report</p>
Author(s) -
Zhan Wang,
Chen-Yang Ye,
Wenli Zhou,
Miaomiao Wang,
Wei Dai,
Jingjing Zheng,
YuanSheng Zang
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s265725
Subject(s) - medicine , colorectal cancer , vemurafenib , regorafenib , oncology , folfiri , cetuximab , liquid biopsy , nivolumab , ipilimumab , progressive disease , progression free survival , immunotherapy , gastroenterology , cancer , disease , metastatic melanoma , overall survival , irinotecan
BRAF V600E mutation represents a group of colorectal carcinoma with poor prognosis. Although treatment strategies have been recommended after clinical investigations, the progression-free survival is short and unsatisfying.