Open Access<p>Identification and Development of Long Non‐coding RNA Associated Regulatory Network in Pancreatic Adenocarcinoma</p>
Author(s) -
Wei Zhu,
Wenzhe Gao,
Yanyao Deng,
Xiao Yu,
Hongwei Zhu
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s265036
Subject(s) - identification (biology) , long non coding rna , pancreatic ductal adenocarcinoma , adenocarcinoma , cancer research , computational biology , rna , biology , medicine , pancreatic cancer , gene , genetics , cancer , botany
Pancreatic adenocarcinoma (PAAD) is the most lethal cancer type around the world. With the in-depth exploration of the function of long non-coding RNAs (lncRNAs), the competing endogenous RNA (ceRNA) mechanism has shown its potential to partially reveal the pathogenesis of PAAD. This study aimed to construct a lncRNA-associated ceRNA network and explore ceRNA regulatory axes with experimental and prognostic value in PAAD.