Open Access<p>LncRNA PART1 Exerts Tumor-Suppressive Functions in Tongue Squamous Cell Carcinoma via miR-503-5p</p>
Author(s) -
Xiqun Zhao,
Yanqing Hong,
Qingyuan Cheng,
Lixin Guo
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s264410
Subject(s) - transfection , cancer research , apoptosis , microrna , western blot , cell growth , luciferase , cell culture , carcinogenesis , cell , microbiology and biotechnology , biology , chemistry , cancer , gene , biochemistry , genetics
Tongue squamous cell carcinoma (TSCC) accounts for one-third of oral cancers. Previous studies had reported that lncRNA/miRNA regulated the biological behaviors of different cancer cells. However, the mechanisms of PART1 in regulating tumorigenesis and TSCC development via targeting miR-503-5p had not been studied.