Open Access<p>The Impact of Smoking on Pulmonary Metastasis in Colorectal Cancer</p>
Author(s) -
Akitsugu Makino,
Masashi Tsuruta,
Koji Okabayashi,
Takashi Ishida,
Kohei Shigeta,
Ryo Seishima,
Akiyoshi Ikebata,
Kaoru Koishikawa,
Hirotoshi Hasegawa,
Masayuki Shimoda,
Koichi Fukunaga,
Tomoko Betsuyaku,
Yuko Kitagawa
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s263250
Subject(s) - medicine , metastasis , colorectal cancer , lung cancer , lung , bronchoalveolar lavage , cancer , inflammation , pathogenesis , pathological , pathology , gastroenterology , oncology
Recently, clinical studies have revealed that smoking can contribute to the poor prognosis of colorectal cancer (CRC) and, additionally, can be a risk factor for pulmonary metastasis of CRC. However, there has been no basic research regarding the underlying molecular mechanism. The purpose of this study was to clarify the mechanism by which smoking causes pulmonary metastasis of CRC.