Open Access<p>MORC4 Promotes Chemoresistance of Luminal A/B Breast Cancer via STAT3-Mediated <em>MID2</em> Upregulation</p>
Author(s) -
Jing Luo,
Shiyan Zeng,
Chao Tian
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s260509
Subject(s) - downregulation and upregulation , cancer research , breast cancer , stat3 , cisplatin , apoptosis , microbiology and biotechnology , cancer , biology , chemistry , medicine , gene , chemotherapy , genetics
MORC4 has recently been characterized as a breast cancer-associated anti-apoptotic oncoprotein. In the current study, we explored its downstream regulation in luminal A/B breast tumors.