Open Access<p><em>Hsa-MiR-590-3p</em> Promotes the Malignancy Progression of Pancreatic Ductal Carcinoma by Inhibiting the Expression of p27 and PPP2R2A via G1/S Cell Cycle Pathway</p>
Author(s) -
Xiasheng Shi,
Weiwei Sheng,
Jia Chen,
Jingtong Tang,
Ming Dong
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s260499
Subject(s) - pancreatic cancer , microrna , western blot , downregulation and upregulation , cancer research , transfection , immunohistochemistry , cell cycle , malignancy , cell , cell growth , biology , cancer , pathology , medicine , gene , biochemistry , genetics
To investigate the effect of miR-590-3p on the malignant biological behavior of pancreatic cancer, and to explore the target genes and pathways directly affected by miR-590-3p , to provide new therapeutic ideas and targets for the study of the diagnosis and treatment of pancreatic cancer.