Open Access<p>Analysis of Differential Expression Proteins of Paclitaxel-Treated Lung Adenocarcinoma Cell A549 Using Tandem Mass Tag-Based Quantitative Proteomics</p>
Author(s) -
Wanchun Zheng,
Shengjie Xu
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s259895
Subject(s) - kegg , proteomics , paclitaxel , a549 cell , tandem mass tag , computational biology , quantitative proteomics , biology , bioinformatics , cancer , cell , gene expression , biochemistry , gene , gene ontology , genetics
Paclitaxel is widely used in the treatment of cancer and has a good effect in the treatment of non-small cell lung cancer. The combination of TMT proteomics and bioinformatics is used to systematically analyze the molecular mechanism of paclitaxel in the treatment of lung adenocarcinoma A549 cell, which is helpful to screen new therapeutic targets.