Open Access<p>Lung Carcinoma Cells Secrete Exosomal MALAT1 to Inhibit Dendritic Cell Phagocytosis, Inflammatory Response, Costimulatory Molecule Expression and Promote Dendritic Cell Autophagy via AKT/mTOR Pathway</p>
Author(s) -
Yanyan Liu,
Yin Zhang,
Ping Lü,
Yihui Ma,
Bo Luo,
Lanxin Xiang,
Wangli Zhang,
Yu He,
Xiaofeng Liang
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s256669
Subject(s) - pi3k/akt/mtor pathway , protein kinase b , dendritic cell , exosome , autophagy , microvesicles , cell growth , flow cytometry , microbiology and biotechnology , chemistry , cancer research , biology , apoptosis , signal transduction , immunology , immune system , microrna , biochemistry , gene
To investigate the potential mechanism underlying the effect of lung carcinoma cell-derived exosomes on dendritic cell function.