Open Access<p>LINC00662 Long Non-Coding RNA Knockdown Attenuates the Proliferation, Migration, and Invasion of Osteosarcoma Cells by Regulating the microRNA-15a-5p/Notch2 Axis</p>
Author(s) -
Shuheng Liu,
Xianghai Meng
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s256464
Subject(s) - gene knockdown , microrna , downregulation and upregulation , osteosarcoma , cancer research , cell growth , chemistry , cell migration , long non coding rna , microbiology and biotechnology , cell , biology , apoptosis , gene , biochemistry
Osteosarcoma (OS) is a frequently occurring malignancy in children and adolescents. In this study, we aimed to investigate the effects of the long non-coding RNA (lncRNA) LINC00662 (LINC00662) in OS and the underlying molecular mechanism.