Open Access<p>A Novel Circular RNA, circ_0005394, Predicts Unfavorable Prognosis and Contributes to Hepatocellular Carcinoma Progression by Regulating miR-507/E2F3 and miR-515-5p/CXCL6 Signaling Pathways</p>
Author(s) -
Chengming Sun,
Guodong Li,
Ming Liu
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s256238
Subject(s) - hepatocellular carcinoma , cancer research , microrna , circular rna , microarray , biology , tumor progression , cancer , gene , gene expression , genetics
Circular RNAs (circRNAs) play a key role in cancer development and progression. Previously, circ_0005394 was found to be highly expressed in hepatocellular carcinoma (HCC) screened by circRNA microarray. However, the research with regard to the functions and mechanisms of circ_0005394 in HCC remains unknown.