Open Access<p>Long Non-Coding RNA LINC00511 Accelerates Proliferation and Invasion in Cervical Cancer Through Targeting miR-324-5p/DRAM1 Axis</p>
Author(s) -
Xin Zhang,
Yuyan Wang,
Anqi Zhao,
Fanshuang Kong,
Li-Peng Jiang,
Jinfeng Wang
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s255067
Subject(s) - cervical cancer , cancer research , carcinogenesis , gene silencing , microrna , medicine , cell growth , western blot , cancer , biology , gene , genetics
Cervical cancer is the second most prevalent female malignance, and human papillomavirus (HPV) infection is the main pathogenic factor of cervical cancer. Emerging evidence has revealed that a number of long non-coding RNAs (lncRNAs) play critical roles in the tumorigenesis and progression of cervical cancer. The aim of this study was to further investigate the precise role of lncRNA LINC00511 in HPV-negative and HPV-positive cervical cancer cells and explore the potential regulatory mechanism.