Open Access<p>Circular RNA Hsa_circ_0004018 Inhibits Wnt/β-Catenin Signaling Pathway by Targeting microRNA-626/DKK3 in Hepatocellular Carcinoma</p>
Author(s) -
Pengfei Zhu,
Han Liang,
Xiangbo Huang,
Zeng Qinglei,
Yanmin Liu,
Jun Lv,
Liang Ming
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s254997
Subject(s) - hepatocellular carcinoma , wnt signaling pathway , microrna , clonogenic assay , cancer research , cell culture , cell growth , microbiology and biotechnology , reverse transcription polymerase chain reaction , biology , chemistry , medicine , messenger rna , signal transduction , gene , biochemistry , genetics
Dysexpression of circular RNAs has been identified in multiple types of cancer. Hsa_circ_0004018 was reported to be significantly downregulated in hepatocellular carcinoma (HCC) and to display HCC-stage-specific expression features. However, the role of hsa_circ_0004018 in HCC progression remains unclear.