Open Access<p>Long Non-Coding RNA TUG1 Promotes Cell Proliferation and Inhibits Cell Apoptosis, Autophagy in Clear Cell Renal Cell Carcinoma via MiR-31-5p/FLOT1 Axis</p>
Author(s) -
Dong Li,
Ying Xiang,
Qi Yang,
Juncheng Yao,
Qiang Dong
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s254634
Subject(s) - clear cell renal cell carcinoma , cell growth , apoptosis , gene knockdown , microrna , cancer research , cell , downregulation and upregulation , long non coding rna , flow cytometry , autophagy , biology , gene silencing , chemistry , microbiology and biotechnology , medicine , renal cell carcinoma , pathology , biochemistry , gene
Clear cell renal cell carcinoma (ccRCC) is a common urological carcinoma in adults. Long non-coding RNA (lncRNA) taurine-upregulated gene 1 (TUG1) has been reported to be involved in the progression of diverse human cancers, including renal cell carcinoma (RCC). However, the biological mechanism of TUG1 was rarely reported in ccRCC.