Open Access<p>Downregulation of Hsa_circ_0000735 Inhibits the Proliferation, Migration, Invasion, and Glycolysis in Non-small-cell Lung Cancer by Targeting miR-940/BMPER Axis</p>
Author(s) -
Weiguo Huang,
Xin Xu,
Mengyang Li,
Weixue Cui,
Guilin Peng
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s253474
Subject(s) - downregulation and upregulation , carcinogenesis , cancer research , cell growth , gene knockdown , cell migration , glycolysis , lung cancer , western blot , biology , cancer , chemistry , cell , medicine , cell culture , endocrinology , metabolism , biochemistry , gene , genetics
Lung cancer is the most commonly diagnosed cancer and the major cause of cancer-related deaths worldwide. The increasing studies have demonstrated that circular RNA (circRNA) was involved in the progression of various cancers, including non-small-cell lung cancer (NSCLC). This study was designed to assess the expression, roles and functional mechanisms of circ_0000735 in NSCLC.