Open Access<p>Circ_0006528 Contributes to Paclitaxel Resistance of Breast Cancer Cells by Regulating miR-1299/CDK8 Axis</p>
Author(s) -
Guoqi Liu,
Zhenxing Zhang,
Song Qu,
Yunshan Guo,
Puqiang Bao,
Huifeng Shui
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s252886
Subject(s) - breast cancer , cancer research , paclitaxel , downregulation and upregulation , cell growth , apoptosis , gene knockdown , flow cytometry , microrna , chemistry , cancer , microbiology and biotechnology , medicine , biology , biochemistry , gene
Circular RNAs (circRNAs) have been reported to be involved in regulating the development of breast cancer. Paclitaxel (PTX) can be used for the chemotherapy of breast cancer. The study aimed to explore the role and mechanism of circ_0006528 in PTX-resistant breast cancer progression.